custom peptide

21st Century Biochemicals - guaranteed peptide fidelity
Custom peptide synthesis

Bruce Merrifield's original synthesis of peptides attached protected amino acids to a growing chain that was covalently bonded to a resin. That unheard of method to synthesize peptides not only won him the Nobel Prize in Chemistry in 1984, but also ushered in a new era of peptide research - scientists were now able to design their own peptides and study them at a previously unattainable scale. Nowadays, you can still do it yourself (see our section on peptide synthesis reagents) or you can order them from a variety of companies as single purified entities, in the form of libraries, optimized for anti-peptide antibody production (MAPS), or even recombinantly produced.

Find below a list of over 100 custom peptide suppliers with a brief categorization of the kind of services that they provide. Please note the meaning of the following descriptors:

  • custom - small scale (typically < 1 gram) synthesis of peptides containing the standard 20 amino acids
  • modified - small scale (typically < 1 gram) synthesis of modified peptides (e.g. N-acetylated, C-amidated, biotinylated, etc.) or peptides containing unusual or unnatural amino acids (e.g., phosphotyrosine, D-amino acids, beta-amino acids, etc.). Please note that each company has its own list of modifications it can incorporate. As a result, you will have to check with the individual company to see what they can do.
  • library - able to produce peptide libraries or peptide arrays for screening purposes - check with the company for the format and degree of purity
  • MAPs - able to produce multiple antigenic peptides (MAPs)

If you are interested regulatory compliant production of GMP peptides (or large scale (> 1 gram) peptide synthesis, non-GMP), see our page on GMP peptide manufacturers.

If you know of a company that should be added or deleted from this section or if you would like to update your company description, please email us. Finally, don't forget to see our Peptide Fun Fact below!

  1. SBS Genetec - (custom, modified, MAPs) - With almost 10 years experience in solid phase peptide synthesis, SBS Genetech is committed to supplying high quality peptides at competitive prices and to providing customers with an extensive range of services and products. Peptides have a 2-3 week turnaround time and are available in purities from crude to 98%. Acetylation or amidation is free of charge. Other areas of speciality include phosphorylated/fluorescein/biotin labeled peptides, cyclic peptides, and MAPs.

  2. 21st Century Biochemicals - (custom, modified, MAPs, library) - epitope mapping, peptides up to 120 amino acids on a mg
    to 500 g scale with purities >98%. Purified peptides are sequenced by CID MSMS to insure fidelity.

  3. Abbiotec - (custom, modified, MAPs, library)

  4. Abgent - (custom, modified, MAPs, library) - specializing in long peptides (50-100+ amino acids) and difficult sequences

  5. ACES Pharma - (custom, modified, library) - including C13 and N15 isotope labeled peptides

  6. AC Scientific - (custom, modified) - cyclic peptides, fluorecein labeled peptides, and peptides containing disulfide bonds

  7. Activotec - (custom, modified, library)

  8. Advanced ChemTech - (custom, modified)

  9. ABR - Affinity BioReagents - (custom, modified)

  10. Alberta Peptide Institute- (custom, modified)

  11. Alpha Diagnostics - (custom, modified)

  12. Alta Bioscience - (custom, modified, MAPs, library)

  13. American Peptide Company - (custom, modified, library)

  14. Anaspec - (custom, modified, MAPs, library)

  15. Antagene - (custom, modified)

  16. Aurora Biomolecules - (custom, modified)

  17. Auspep - (custom, modified, MAPs)

  18. Bachem - (custom, modified, library) - with experience in the synthesis of very long peptides up to small proteins

  19. BAM Biotech Company - (custom, modified)

  20. Biomatik - (custom, modified, library)

  21. BioConcept - (custom, modified)

  22. Biomer Technology - (custom, modified)

  23. BIOMOL International (Affiniti Research Products) - (custom, modified, MAPs, library) - unpurified peptide panels for screening purposes

  24. Biopeptide - (custom)

  25. Biosight - (custom, modified, MAPs, library)

  26. Bio-Synthesis - (custom, modified, library) - with experience in the synthesis of long peptides (up to, but not limited to 100 residues)

Peptide Fun Fact: The Fmoc group is the most common amino acid protecting group using today in the solid phase synthesis of peptides.  However, the use of this group is relatively new in the history of peptide synthesis.  Peptides were originally produced more laboriously in solution where a strategy of amine protection followed by coupling then amine deprotection had to be followed.  Developed by Bergman and Zervas in 1932 [Ber. Dtsch. Chem. Ges. 65 (1932) 1192], the Cbz group was the first amine protecting group to be used and was removed using catalytic hydrogenolysis.  The acid labile Boc group was developed by Carpino in 1957 [J. Am. Chem. Soc. 79 (1957) 98] and was the second popular protection strategy to produce peptides in solution.  The use of the fluorenylmethoxycarbonyl (Fmoc) group, also invented by Carpino [J. Am. Chem. Soc. 92 (1970) 5748], was popularized in the 1980s along with its use on automated peptide synthesizers.

  1. California Peptide Research - (custom, modified)

  2. Cambridge Research Biochemicals - (custom, modified)

  3. CanPeptide - (custom, modified, MAPs)

  4. CASLO - (custom, modified)

  5. Cell Essentials - (custom)

  6. Celtek Peptides - (custom, modified)

  7. ChemPep - (custom, modified)

  8. Chengdu CP Biochem Company - (custom, modified)

  9. Chengdu Kaijie Bio-pharmaceutical - (custom, modified)

  10. Chinese Peptide Company - (custom, modified, library) - peptide arrays, peptides in 96 plate, FRET peptides

  11. Chinatech Peptide - (custom, modified)

  12. Chromatide - (custom, modified, library)

  13. Combinix- (custom) - specializing in the synthesis of FRET peptides

  14. Commonwealth Biotechnologies - (custom, modified)

  15. CovalAb UK - (custom, modified, library) - functionalized microtiter plates for peptide immobilisation with or without peptides

  16. CPC Scientific - (custom, modified, library)

  17. CS Bio - (custom, modified) - specializing in in difficult sequences

  18. CSS-Albachem - (custom, modified)

  19. DigitalGene Biosciences - (custom, modified)

  20. DNA2.0 - (custom) - any length of sequence by recombinant means

  21. Enzyme Research Laboratories - (custom)

  22. Eurogentec - (custom, modified, MAPs, library)

  23. Eurosequence - (custom, modified)

  24. Fusion Antibodies - (custom, MAPs)

  25. Gallus Immunotech - (custom)

  26. Gene Gateway - (custom, modified)

  27. GenoMechanix - (custom, modified)

  28. Genosphere Biotechnologies - (custom, modified)

  29. GenScript - (custom, modified, library) - extra long sequences (>50 residues) can be produced using recombinant techniques. In addition, they can synthesize difficult sequences using microwave technology.

  30. Gentaur - (custom)

  31. GL Biochem - (custom, modified)

  32. Global Peptide - (custom, modified)

  33. GT Biochem - (custom, modified, library)

  34. Hanhong Chemical - (custom, modified)

  35. INBIOS - (custom, modified, library) - including glycosylated peptide synthesis

  36. Innovagen - (custom, modified, MAPs)

  37. Invitrogen - (custom, modified)

  38. Intavis - (custom, modified)

  39. Jerini Peptide Technologies (JPT) - (custom, modified, library) - peptide arrays that target kinases, phosphatases, and proteases as well as custom arrays

  40. LAE Biotech International - (custom, modified)

  41. Lonza - (custom, modified) - including pegylated, glycosylated, D-aminoacid containing peptides. Lonza technology includes three peptide manufacturing platforms (solid-phase, liquid-phase, and recombinant DNA)

  42. Macromolecular Resources - (custom, modified)

  43. MedProbe - (custom, modified)

  44. Midwest Bio-Tech - (custom, modified, library) - stable isotope incorporation as well

  45. MilleGen - (custom, modified)

  46. Mimotopes - (custom, modified, library) - PepSets™ - 96 well peptide libraries, pin-bound or in solution

  47. NeoMPS - (custom, modified)

  48. New England Peptides - (custom, modified, library) - phage display peptide libraries

  49. Novabiochem - (custom, modified)

  50. Open Biosystems - (custom, modified)

  51. Orbigen - (custom)

  52. ORPEGEN Pharma - (custom, modified)

  53. Pepceuticals - (custom, modified, library) - including cyclic and radiolabeled peptides

  54. PepMetric Technologies - (library)

  55. Pepscan Systems - (custom, library) - solid phase bound peptide libraries

  56. Peptide 2.0 - (custom, modified, library)

  57. Peptide Laboratory - (custom, modified, library)

  58. Peptides International - (custom, modified, MAPs, library)

  59. Peptide Synthetics - (custom, modified, MAPs) - modified peptides include the production of urea containing peptides and peptide aldehydes

  60. Peptron - (custom, modified, library)

  61. Phoenix Peptides - (custom, modified)

  62. Pi Proteomics - (custom, modified, MAPs)

  63. PolyPeptide Laboratories - (custom)

  64. Princeton BioMolecules Corporation - (custom, modified, MAPs, library) - N15/C13 labeled peptides and solid phase bound peptide libraries

  65. Proimmune - (custom, modified, library)

  66. QCB - Quality Controlled Biochemicals - (custom, modified)

  67. Rapp Polymere - (custom)

  68. rPeptide - (custom, modified) - synthetic and recombinant methods for longer and difficult peptides

  69. Schafer-N - (custom, modified, library) - phage display screening

  70. Scilight Biotechnology - (custom, modified)

  71. Severn Biotech - (custom, modified, MAPs)

  72. Sigma-Genosys (Sigma-Aldrich) - (custom, modified, library) - PEPscreen™ custom libraries and SPOTS protein mapping technology

  73. Sussex Research Laboratories - specializing in the synthesis of glycopeptides

  74. SynBioSci Corporation - (custom, modified, library)

  75. Thermo Biopolymers - (custom, modified, MAPs) - and custom heavy peptides for direct protein quantification by LC-MS

  76. Phoenix Peptides - (custom, modified)

  77. Tufts University Core Facility - (custom, modified, library)

  78. United Biochemical Research - (custom)

  79. United States Biological - (custom, modified, MAPs)

  80. Washington Biotech - (custom, modified)

  81. Xaia Custom Peptides - (custom, modified)

  82. Zhongbang Pharma-Tech Company - (custom, modified)