1. Amino acid basics - a well done Flash animation on amino acids, peptide synthesis, and secondary structure

2. Amino acid metabolism - on the catabolism (biosynthesis) of amino acids

3. Amino acid overview - a basic reference covering the structure and chemical properties of amino acids. Individual amino acids and other terms are hyperlinked to more in depth descriptions.

4. Amino acid properties - a good references page describing general properties (e.g., structures and protecting group masses), suggested amino acid substitutions, chemical properties (e.g., chemical classification and hydrophobicity), structural properties (e.g., peptide bond angles and Chou-Fasman parameters), and genetic properties. Original references for all the tables are also provided. From PROWL - a resource for protein chemistry and mass spectrometry.

5. Bioactive Polypeptide Database - a database that contains three sections to find a bioactive peptide by peptide sequence, gene sequence, or a reference search

6. Biosynthesis of amino acids

7. Botany Online: Basic Metabolism - choose your amino acid, its metabolism or degradation, and your organism to view complete metabolic pathways. The front page comes with a great overview of plant amino acid metabolism.

8. Bruce Merrifield - a brief biography - the father of solid phase peptide chemistry

9. A de novo peptide sequencing tutorial - a informative website devoted to how to interpret mass spectrometry fragmentation for the purpose of peptide identification. There is a useful glossary explaining terms like b and y ions, example spectra, helpful references, and tables of amino acid masses, dipeptide masses, and possible conflicting masses.

10. How Does Mass Spectrometry Identify Proteins?

11. How to identify peptides with proteomics - how to use mass spectrometry to identify peptides from proteins

12. Mayflower Web Gateway Site - an internet portal for molecular and life scientists which includes a detailed calendar of peptide related meetings, service providers, suppliers, etc...

13. The Medical Biochemistry Page - a page with a variety of topics related to the title including amino acid metabolism, specialized products of amino acids, and the basic chemistry of biomolecules.

14. Molecular Expressions: The Amino Acid Collection - an overview of some of the interesting roles and properties of the 20+ naturally occuring amino acids. Each is accompanied by a groovy picture.

15. Nomenclature and Symbolism for Amino Acids and Peptides - from the International Union of Pure and Applied Chemistry and the International Union of Biochemistry and Molecular Biology.

16. Peptide Antigen Database - from the Protein Lounge. This database contains antigenic peptide targets against all known protein sequences throughout a variety of organisms. All peptide targets are linked to the Protein lounge online hydroplotting tool, which allows you to view an interactive version of the protein sequence on a hydrophilicity/phobicity plot.

17. Peptide Explorer - from Sigma-Aldrich: a great reference containing categories of related peptides (e.g. substrates, obesity peptides, immunomodulators, and many more) that Sigma-Aldrich sells. Find your peptide of interest, click on the product number, and a variety of chemistry related information appears such as sequence, chemical formula, molecular weight, and relevant literature references.

18. Peptide Hormones - a colorful reference containing data on the title subject such as a descriptive table of peptide hormones, the structure and function of hormones, and detailed information on the function of specific peptide hormones (e.g. vasopressin and oxytocin, natriuretic hormone, calcitonin, etc...).

19. Peptide Sequencing and Synthesis - a mechanistic overview of Edmand degradation and DCC coupling

20. Protein Synthesis - an overview

21. Peptide Synthesis Tips and Procedures - from EMD/Merck. A series of very informative brochures (downloadable as PDF files) on such areas as coupling protocols, the synthesis of long or difficult to synthesize peptides, loading and cleavage protocols, peptide ligation and labeling, and much more. This is an interesting place to visit if you are into the chemistry of solid phase peptide synthesis.

22. Proteins, peptides, and amino acids - a nicely illustrated and descriptive overview which covers: α-Amino Acids, Reactions of Amino Acids, Synthesis of Amino Acids, Peptides & Proteins, The Primary Structure of Peptides, Secondary & Tertiary Structure of Large Peptides and Proteins, and Peptide Synthesis

23. Signal Peptide Database (SPdb) - a database of experimentally verified signal peptides. Amongst other criteria, the authors compiled the sequences by extracting entries from Swiss-Prot that contained the key work "signal" in the feature table.

24. Stanley Miller - two webistes on his classic experiment on the abiotic and primordial synthesis of amino acids: #1 and #2

Peptide Societies